Therapy of Systemic Rheumatic Disorders by Leo Van de Putte, Putte, Richard H. Williams

By Leo Van de Putte, Putte, Richard H. Williams

Provides the newest details at the pharmacotherapy of systemic rheumatic disorders-including polyarthritis, spondyloarthropathies, and connective tissue diseases-highlighting the significance of early prognosis, ailment review, and tracking.

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Sample text

Rheumatology Unit, Royal Free Hospital, London, United Kingdom Page x B. A. C. D. D. P. Department of Rheumatology, St. George Hospital, and University of New South Wales, Sydney, New South Wales, Australia Michael J. P. P. Rheumatology and Rehabilitation Research Unit, University of Leeds, Leeds, United Kingdom Dafna D. C. Centre for Prognosis Studies in the Rheumatic Diseases, The University of Toronto, and Toronto Hospital, Toronto, Ontario, Canada Michael J. B. P. D. Division of Rheumatology, Department of Medicine, University Hospital of Geneva, Geneva, Switzerland E.

Clinical Trials Revisited Harold E. Paulus and Ken J. Second-line Agent Treatment: When and Whom David L. Aggressive Treatment of Rheumatoid Arthritis: When, Whom, and How Graciela S. Hydroxychloroquine Howard Bird and Ann W. D-Penicillamine Howard Bird and Ann W. Gold Therapy Anne McEntegart and Hilary A. Cytotoxics (Azathioprine, Chlorambucil, and Cyclophosphamide) Philip J. Combination Disease-modifying Antirheumatic Drug Therapy in Rheumatoid Arthritis H. When to Stop Second-line Drugs: Risk/Benefit Ratio of Continuation Versus Cessation in Patients with Rheumatoid Arthritis in Remission S.

Advanced molecular biological techniques are now available, not only to unravel the disease process but also to construct agents that interfere with relevant pathogenetic processes. The recent successes with monoclonal antibodies against TNF-α are just one example of what may await us in the future. Page iv Although the emphasis has been on treatment of rheumatoid arthritis, definite and welcome improvements have been made in the treatment of other systemic autoimmune rheumatic disorders. For instance, we now have a new taxonomy of vasculitides, and antibodies like ANCA now allow for better disease classification and monitoring.

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