Systemic Lupus Erythematosus: A Companion to Rheumatology by George C. Tsokos, Caroline Gordon, Josef S. Smolen
By George C. Tsokos, Caroline Gordon, Josef S. Smolen
This new significant other to Hochberg et al.'s Rheumatology masterwork presents new insights into the motives, detection and remedy of this demanding sickness. during this cutting-edge source, you will find 'one cease' assurance of the entire most modern clinical and scientific advancements in SLE: new strategies in epidemiology, affliction job measures and results; new recommendations in immunoregulation, genetic and pathogenic mechanisms; new knowing and novel presentation of the strategies of tissue/organ harm; complete assurance of medical beneficial properties; and the very newest suggestions in treatment.Provides the very newest realizing of the pathogenesis of SLE. Distills present knowing of the mobile, molecular, genetic and environmental elements that instigate and force the disease.Includes complete insurance of medical good points, together with fatigue, organ method manifestations, overlap syndromes, infections, and more.Conveys the very most modern realizing of mechanisms of tissue harm, together with immune complexes, antibodies, and different mechanisms that bring about organ damage.Contains professional dialogue of tactics which are accountable for tissue damage - a trademark of this text.Incorporates the most recent remedy modalities, together with steroids and non-steroidals, cytotoxic drug therapy, PAP's, and remedies at the horizon.Discusses the newest therapies on ailment editing or illness controlling brokers.
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Additional resources for Systemic Lupus Erythematosus: A Companion to Rheumatology
Polyarticular arthritis with loss of function receives an A score, and so is weighted to score more heavily than simple arthritis, which engenders a B score) (see Appendix E). By assigning numerical values to the activity scores for each organ system, (A=9, B=3, C=1, D or E=0) it is possible to calculate a global activity score ranging from 0 to 72 (albeit in practice scores as high as 27 are rare). 12,13 In the last version, two additional systems—gastrointestinal and ophthalmic—were added (see Appendices G, H, and I).
Ramsey-Goldman R, Isenberg DA. Systemic lupus erythematosus measures. Arthritis Care Res 2003;49(Suppl 5):S225-33. 5. Haq I, Isenberg DA. How does one assess and monitor patients with systemic lupus erythematosus in daily clinical practice? Best Pract Res Clin Rheumatol 2002;16:181-94. 6. Symmons DPM, Coppock JS, Bacon PA, et al. Development and assessment of a computerized index of clinical disease activity in systemic lupus erythematosus. Q J Med 1988;69:927-37. 7. Hay EM, Bacon PA, Gordon C, et al.
45. Bernatsky S, Boivin JF, Joseph L, et al. An international cohort study of cancer in systemic lupus erythematosus. Arthritis Rheum 2005;52:1481-1490. 46. Pons-Estel BA, Catoggio LJ, Cardiel MH, et al. The GLADEL multinational Latin American prospective inception cohort of 1,214 patients with systemic lupus erythematosus: ethnic and disease 48. 49. 50. 51. 52. 53. 54. 55. 56. 57. 58. 59. 60. Ward MM, Pyun E, Studenski S. Long-term survival in systemic lupus erythematosus. Patient characteristics associated with poorer outcomes.