Respiratory Physiology: The Essentials by John B. West MD PhD

By John B. West MD PhD

Widely thought of the most desirable for the educating and studying of respiration body structure, this absolutely up to date 9th version comprises key issues for every bankruptcy and multiple-choice overview questions and solutions with complete factors. on hand on-line through thePoint, animations support to elucidate fairly tricky ideas and supply a visible part to be used in the course of guide or review.

 

--NEW offers rationales for all questions, in addition to factors for every solution choice

--Provides eighty two essential-to-know, multiple-choice overview questions which seem on the finish of every chapter

--Features an Appendix of significant equations

--Supports studying via chapter-opening studying targets and introductory fabric, in addition to Key strategies summaries on the finish of every chapter

--Includes on-line assets similar to query financial institution, animations, and entire textual content for students

--Includes animations online--8 in total--via thePoint to demonstrate rather difficult concepts

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Extra resources for Respiratory Physiology: The Essentials

Sample text

Next, we distinguish between diffusion- and perfusionlimited gases. Oxygen uptake along the pulmonary capillary is then analyzed, and there is a section on the measurement of diffusing capacity using carbon monoxide. The finite reaction rate of oxygen with hemoglobin is conveniently considered with diffusion. Finally, there is a brief reference to the interpretation of measurements of diffusing capacity and possible limitations of carbon dioxide diffusion. indd d 24 24 6/18/2011 6/18/ 8/2 /2011 9:49:15 9:49:15 AM Diffusion 25 In the last chapter, we looked at how gas is moved from the atmosphere to the alveoli, or in the reverse direction.

Drugs that can relax smooth muscle in the pulmonary circulation include acetylcholine and isoproterenol. Pulmonary Vascular Resistance • Is normally very small • Decreases on exercise because of recruitment and distension of capillaries • Increases at high and low lung volumes • Increases with alveolar hypoxia because of constriction of small pulmonary arteries ▲ Measurement of Pulmonary Blood Flow . The volume of blood passing through the lungs each minute (Q ) can be calculated. using the Fick principle.

For these reasons, the term transfer factorr is sometimes used (particularly in Europe) to emphasize that the measurement does not solely refl flect the diffusion properties of the lung. ▲ CO2 Transfer Across the Pulmonary Capillary We have seen that diffusion of CO2 through tissue is about 20 times faster than that of O2 because of the much higher solubility of CO2 (Figure 3-1). At first sight, therefore, it seems unlikely that CO2 elimination could be affected fi by diffusion difficulties, fi and indeed, this has been the general belief.

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