Pulmonary Pathology by R. Rao MD, Cesar Moran MD, Saul Suster MD
By R. Rao MD, Cesar Moran MD, Saul Suster MD
Intended for busy practitioners, Pulmonary Pathology is a pithy, pocket-sized advisor to all the key pulmonology entities and diagnoses that pulmonologists see in day-by-day perform. It addresses non-neoplastic stipulations together with Infections, Granulomatous ailments, Acute Lung damage, Idiopathic Interstitial Pneumonias, Vasculitis, Histiocytoses, Lung Pathology in Systemic ailments, Transplant-Related Lung Pathology, and Miscellaneous Non-Neoplastic stipulations. Neoplasia entities comprise Benign Epithelial Neoplasia, Pre-Invasive Neoplasia, Squamous phone Carcinoma, Adenocarcinoma, Neuroendocrine Neoplasia, different Epithelial Neoplasia, Mesenchymal Neoplasia, Lymphoproliferative problems, Pleural Tumors, Metastatic Tumors, and Tumor-Like stipulations. The ebook encompasses a bulleted layout replete with illustrations for fast details retrieval. it will likely be a convenient precis and speedy reference for pulmonary pathology citizens and should function a transportable refresher path for more matured pathologists.
The Demos Surgical Pathology Guides sequence provides in precis and visible shape the elemental wisdom base that each working towards pathologist wishes each one operating day. sequence volumes disguise the most important uniqueness components of surgical pathology, and insurance emphasizes the most important entities and diagnoses that pathologists will see in perform, and they needs to comprehend even if in education or perform. The emphasis is at the simple morphology with more recent concepts represented the place they're usually used. The sequence offers a convenient precis and quickly reference that any pathology resident or fellow will locate precious. skilled practitioners will locate the sequence precious as a conveyable refresher direction or evaluate tool.
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Meant for busy practitioners, Pulmonary Pathology is a pithy, pocket-sized advisor to all the key pulmonology entities and diagnoses that pulmonologists see in day-by-day perform. It addresses non-neoplastic stipulations together with Infections, Granulomatous illnesses, Acute Lung damage, Idiopathic Interstitial Pneumonias, Vasculitis, Histiocytoses, Lung Pathology in Systemic ailments, Transplant-Related Lung Pathology, and Miscellaneous Non-Neoplastic stipulations.
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Tuberculosis infection. Ziehl–Neelsen stain shows occasional long, thin, beaded acid-fast bacilli. 16 Chapter 1: Infections C D E FIGURE 1-4 Chapter 1: Infections 17 Granulomatous Diseases Sarcoidosis Hypersensitivity Pneumonitis Bronchocentric Granulomatosis 2 Sarcoidosis DEFINITION ■■ Sarcoidosis is a multisystem granulomatous disease that affects the lungs frequently. ■■ Granuloma formation in affected organs is driven by a type IV hypersensitivity response to an as yet unknown antigen. ■■ The term sarcoidosis is derived from “sarcos” (Greek—Fleshy), alluding to the fleshy appearance of affected organs.
CLINICAL FEATURES ■■ A vast majority (>90%) of patients are current or past cigarette smokers. ■■ Average age of onset is 40 years with a male to female ratio of 2:1. ■■ Clinical symptoms are subacute in nature, lasting weeks or months, with dyspnea, cough, and/or chest pain. ■■ The cornerstone of treatment is smoking cessation, although many patients require and have variable response to steroid therapy. ■■ Overall prognosis is better than for UIP and fibrosing variant of NSIP. PATHOLOGIC FINDINGS ■■ In contrast to other patterns of IIP, where the changes occur predominantly in the interstitial compartment, the hallmark of DIP is diffuse exudation of intra-alveolar macrophages, with very mild interstitial inflammation and fibrosis and without architectural remodeling (Figure 4-3A).
There is uniform interstitial widening by a chronic inflammatory infiltrate. (B) Nonspecific interstitial pneumonia, fibrosing variant. There is uniform loose to dense interstitial fibrosis with a minor interstitial inflammatory component. (C) Nonspecific interstitial pneumonia. Minor features include foci of organizing pneumonia. 46 Chapter 4: Idiopathic Interstitial Pneumonias A B C FIGURE 4-2 Chapter 4: Idiopathic Interstitial Pneumonias 47 Nonspecific Interstitial Pneumonia (continued) DIFFERENTIAL DIAGNOSIS ■■ UIP may be difficult to differentiate from the fibrosing variant of NSIP, which has uniform dense or loose interstitial fibrosis without the heterogeneity of UIP.