Polymyalgia Rheumatica and Giant Cell Arteritis by Jozef Rovensky, Burkhard F. Leeb, Howard Bird, Viera

By Jozef Rovensky, Burkhard F. Leeb, Howard Bird, Viera Štvrtinová, Richard Imrich

This monograph deals present insights into polymyalgia rheumatica and sizeable telephone arteritis. either illnesses are general for complex age and their incidences raise with getting older. Early analysis and quick therapy can keep essentially the most beneficial senses - our imaginative and prescient. This publication presents an outline at the pathophysiology, their genetic, immunologic, endocrinologic mechanism of those illnesses, yet most crucial it bargains with cutting-edge analysis and present remedy in aged with the try and diagnose and deal with those rheumatic illnesses even speedier and extra successfully sooner or later.

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Subtle inflammatory changes may be visible in the synovial tissue: the synovial fluid shows a slight inflammatory activity. 32 5 J. Rovenský, R. Imrich References 1. 2. 3. 4. 5. Uddhammar A, Sundqvist KG, Ellis B et al. Cytokines and adhesion molecules in patients with polymyalgia rheumatica. Br J Rheumatol 1998; 37: 766–769. Balin H, Abdelmouttaleb I, Belmin J et al. Arterial wall production of cytokines in giant cell arteritis: results of a pilot study using human temporal artery cultures. J Gerontol A Biol Sci Med Sci 2002; 57: 241–245.

In: The vasculitides. Science and practice. M. Ansell, P. A. T. Lie, H. Yazici), Chapman and Hall Medical, London – Glasgow – Weinheim – New York – Tokyo – Melbourne – Madras 1996, 171–180. : The epidemiology of giant cell arteritis including temporal arteritis and polymyalgia rheumatica. , 24, 1981, 899–904. , Muller-Hulsbeck, S. et al: Balloon angioplasty of upper extremity in patients with extracranial giant cell arteritis. Ann. Rheum. , 65, 2006, 9, 1124–1130. : Increased incidence of aortic aneurysm and dissection in giant cell (temporal) arteritis.

Functional Profile of Tissue-infiltrating and Circulating CD68+ Cells in Giant Cells Arteritis. J Clin Invest 1994; 94: 1134–1140. Weyand CM, Hicok CK, Hunder GG, Goronzy JJ. The HLA-DRB1 locus as a genetic component in giant cell arteritis. Mapping of a disease-linked sequence motif to the antigen-binding site of the HLA-DR molecule. J Clin Invest 1992; 90: 2355–2361. Weyand CM, Hunder NN, Hicok CK et al. HLA-DRB1 alleles in polymyalgia rheumatica, giant cell arteritis and rheumatoid arthritis.

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