Oxidation of Alcohols to Aldehydes and Ketones by Gabriel Tojo
By Gabriel Tojo
The purpose of this booklet is to aid humans acting regimen operations in natural Synthesis in a laboratory. This publication, the 1st one in a chain, specializes in the oxidation of alcohols to aldehydes and ketones. most likely, this can be an important regimen operation in natural Synthesis.
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Additional info for Oxidation of Alcohols to Aldehydes and Ketones
4. Pyridinium Dichromate (PDC) It is important to stress the fact that no fragmentation needs to occur wherever a stable carbocation can be formed. 184 O O O N OH O O O O N PDC SO2Me O SO2Me O O O 76% Ref. 184a No fragmentation occurs regardless of the very stabilized carbocations that it would produce. Sometimes, treatment of primary alcohols with PDC leads to the formation of dimeric esters186 arising from the oxidation of acyclic hemiacetals, formed by reaction of the starting alcohol with an intermediate aldehyde.
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