Oxidation of Alcohols to Aldehydes and Ketones by Gabriel Tojo

By Gabriel Tojo

The purpose of this booklet is to aid humans acting regimen operations in natural Synthesis in a laboratory. This publication, the 1st one in a chain, specializes in the oxidation of alcohols to aldehydes and ketones. most likely, this can be an important regimen operation in natural Synthesis.

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4. Pyridinium Dichromate (PDC) It is important to stress the fact that no fragmentation needs to occur wherever a stable carbocation can be formed. 184 O O O N OH O O O O N PDC SO2Me O SO2Me O O O 76% Ref. 184a No fragmentation occurs regardless of the very stabilized carbocations that it would produce. Sometimes, treatment of primary alcohols with PDC leads to the formation of dimeric esters186 arising from the oxidation of acyclic hemiacetals, formed by reaction of the starting alcohol with an intermediate aldehyde.

Tetrahedron Lett. 1987, 28, 239. ; Tetrahedron Lett. 1987, 28, 671. ; Rabanal, R. Chem. 1987, 65, 339. e) Pirrung, M. ; Thomson, S. Chem. 1988, 53, 227. ; Q. ; Sulikowski, G. ; Tetrahedron 2002, 58, 4403. ; Zannetti, M. Chem. 1995, 60, 7870. 37 a) White, J. ; Jayasinghe, L. ; Tetrahedron Lett. 1988, 29, 2139. ; Tetrahedron Lett. 1987, 28, 3091. 38 a) Smith, A. ; Pitsinos, E. ; Scarlato, G. ; Nicolaou, K. Soc. 1993, 115, 7612. Bull. 1987, 35, 996. Bull. 1986, 34, 4629. 39 a) Danishefsky, S. ; Selnick, H.

A) Ref. 46b. b) Anderson, R. Chem. 1985, 50, 4781. ; Tetrahedron Lett. 1985, 26, 2693. ; Tetrahedron Lett. 1989, 30, 103. Evans, D. ; Bender, S. ; Tetrahedron Lett. 1986, 27, 799. , R. ; Tagat, J. ; Johnston, B. ; Heterocycles 1987, 25, 33. a) Ref. 97. b) Shing, T. K. Chem. 2000, 65, 7059. c) Holum, J. Chem. 1961, 26, 4814. Chem. 1977, 42, 813. Walba, D. ; Stoudt, G. ; Tetrahedron Lett. 1982, 23, 727. ; Robins, M. ; Tetrahedron 1984, 40, 125. 4. 4. Pyridinium Dichromate (PDC) O PyH O O Cr O Cr O O PyH O The slow addition of one equivalent of pyridine on a concentrated aqueous solution of CrO3 leads to the formation of pyridinium dichromate (PDC), which can be precipitated by the addition of 4 volumes of acetone per volume of water and cooling at À208C.

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