Organic Synthesis: Concepts, Methods, Starting materials by Fuhrhop J., Penzlin G.

By Fuhrhop J., Penzlin G.

Show description

Read or Download Organic Synthesis: Concepts, Methods, Starting materials PDF

Best organic chemistry books

Biochemistry (6th Edition)

Detect how the most recent advancements in biotechnology, genomics, and proteins without delay have an effect on your existence with Campbell/Farrell? s best-selling biochemistry textual content. recognized for its logical association and applicable intensity of assurance, BIOCHEMISTRY, 6th version, balances medical element with clarity that?

Organic reaction mechanisms

Offers the latest advancements in natural chemistry. Compiled via well-respected editors with a long time of proper event.

Microwaves in Organic Synthesis

The lengthy awaited re-creation of this complete two-volume reference has been thoroughly up-to-date and increased through 30% to incorporate chapters on ionic drinks, carbohydrate chemistry, multicomponent reactions, strong section peptide synthesis, carbon nanotubes and fullerenes. Written by way of the main eminent scientists of their respective fields, the chapters, which counterpoint each other, now additionally comprise 8 new fields of software, akin to heterocyclic chemistry, cycloadditions and carbohydrate chemistry.

Extra resources for Organic Synthesis: Concepts, Methods, Starting materials

Example text

The polymerization is carried out in a sealed container. After completion of the polymerization, the container is broken and the polymer monolith is coarsely crushed, then ground and sieved to obtain particles of appropriate size range. The template molecules are extracted from the polymer. Finally, the polymer particles are dried. This protocol is time- and labor-intensive and produces large amounts of particles of unwanted size fractions. 5). 5 Scanning electron micrograph of irregular MIP particles.

The rebinding, however, relies on noncovalent interactions. When the covalently bound template moiety is cleaved from the MIP, a functional group capable of interacting non-covalently with the target molecule is left behind in the polymer at the cleavage site. The semi-covalent approach has been used successfully for the preparation of MIPs selective for p-aminophenylalanine ethyl ester [69], phenol [70] and triazines [71] among others. The cavity left behind after cleaving off the covalently bound template moiety is often too small to accommodate the target molecule during non-covalent rebinding.

Meldal, M. and Bock, K. (1999) Journal of the American Chemical Society, 121, 5459–66. 44 Atherton, E. C. (1989) Solid Phase Peptide Synthesis: A Practical Approach, IRL Press, Oxford. 45 Kempe, M. and Barany, G. (1996) Journal of the American Chemical Society, 118, 7083–93. 46 Meldal, M. (1992) Tetrahedron Letters, 33, 3077–80. 47 Renil, M. and Meldal, M. (1996) Tetrahedron Letters, 37, 6185–8. 48 Buchardt, J. and Meldal, M. (1998) Tetrahedron Letters, 38, 8695–8. , Meldal, M. and Bock, K. (1999) Chemistry – A European Journal, 5, 1088–95.

Download PDF sample

Rated 4.09 of 5 – based on 25 votes