Neonatal Respiratory Distress by Philip M Farrell (Eds.)

By Philip M Farrell (Eds.)

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1981). Effect of ventilation on the surface properties of the lung. 2. Clinical Relevance of Pulmonary Surfactant 24. 25. 26. 27. 28. 29. 30. 31. 32. 21 In "Progress in Respiration Research: Clinical Importance of Surfactant Defects" (P. ), pp. 194-206. Karger, Basel. Pattle, R. E. (1955). Properties, function and origin of the alveolar lining layer. Nature (Lon­ don) 175, 1125-1126. Pattle, R. , Kratzing, C. C , Parkinson, C. , Robertson, R. D . , Robards, G. , Currie, J. , Parsons, J. , and Sutherland, P.

29. 30. 31. 32. 21 In "Progress in Respiration Research: Clinical Importance of Surfactant Defects" (P. ), pp. 194-206. Karger, Basel. Pattle, R. E. (1955). Properties, function and origin of the alveolar lining layer. Nature (Lon­ don) 175, 1125-1126. Pattle, R. , Kratzing, C. C , Parkinson, C. , Robertson, R. D . , Robards, G. , Currie, J. , Parsons, J. , and Sutherland, P. D. (1979). Maturity of fetal lungs tested by production of stable microbubbles in amniotic fluid. Br. J. Obstet. GynecoL 86, 615-622.

6. Pulmonary hyaline membranes, accompanied by collapse of terminal air sacs and dilitation of respiratory bronchioles, may be helpful in confirming the diagnosis at autopsy, but should not be considered the sine qua non of HMD, particularly in newborns succumbing before 6 hours or after 96 hours of age. For research purposes, the method of Hobel et al. {32a) may be utilized to establish a numerical score for the diagnosis of hyaline membrane disease. This method provides an objective index of respiratory distress syndrome based on clinical and radiographic features, as well as arterial blood gas data.

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