Nanomaterial-Based Drug Delivery Carriers for Cancer Therapy by Tao Feng, Yanli Zhao

By Tao Feng, Yanli Zhao

This short summarizes types of natural and inorganic nanomaterials for drug supply in melanoma treatment. It highlights that accurately designed nanomaterials often is the next-generation healing brokers for melanoma treatment.

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Small 8:281−290 Tian Q, Tang M, Sun Y, Zou R, Chen Z, Zhu M, Yang S, Wang J, Wang J, Hu J (2011) Hydrophilic flower-like CuS superstructures as an efficient 980 nm laser-driven photothermal agent for ablation of cancer cells. Adv Mater 23:3542–3547 Tong L, Zhao Y, Huff TB (2007) Gold nanorods mediate tumor cell death by compromising membrane integrity. Adv Mater 19:3136–3141 Tran V, Soklaski R, Liang Y, Yang L (2014) Layer-controlled band gap and anisotropic excitons in few-layer black phosphorus.

1) Residual metal catalysts. The remaining iron and nickel metals in the synthesized CNTs could produce free radicals in cells to cause obvious cytotoxicity, as confirmed by cell experiments. To remove residual metals, CNTs can be dispersed in mixed acids with refluxing. (2) CNT length. The length of CNTs is usually in the range from several to tens of micrometers, while studies have found that CNTs with length less than 200 nm are easier to accumulate inside cells. To truncate CNTs into short pieces, CNTs should be purified via multiple filtering.

2012b)] can also be used for the synthesis of carbon dots. Carbon dots are also a new class of fluorescent materials with emissive wavelength from blue to near-infrared. The wide fluorescence range can be obtained by the excitation-dependent emission or different synthetic and purification methods. Carbon dots have high quantum yield and good photostability to overcome the drawbacks of photobleaching for organic dyes or photoblinking for quantum dots. 38 3 Nanomaterial-Based Drug Delivery Carriers for Cancer Therapy Benefited from these excellent properties, carbon dots can be utilized for bioimaging both in vitro and in vivo.

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