Layer-by-layer films for biomedical applications by Catherine Picart, Frank Caruso, Jean-Claude Voegel, Gero
By Catherine Picart, Frank Caruso, Jean-Claude Voegel, Gero Decher
The layer-by-layer (LbL) deposition process is a flexible method for getting ready nanoscale multimaterial motion pictures: the fabrication of multicomposite motion pictures through the LbL process permits the mix of actually 1000s of alternative fabrics with nanometer thickness in one machine to acquire novel or enhanced functionality. within the final 15 years the LbL procedure has noticeable huge advancements and has now reached some extent the place it truly is commencing to locate functions in bioengineering and biomedical engineering.
The booklet offers an intensive review of functions of the LbL procedure within the context of bioengineering and biomedical engineering the place the final years have witnessed super development. the 1st half familiarizes the reader with the specifics of cell-film interactions that must be taken into consideration for winning program of the LbL procedure in organic environments. the second one half specializes in LbL-derived small drug supply structures and antibacterial brokers, and the 3rd half covers nano- and microcapsules as drug vendors and biosensors. The fourth and final half makes a speciality of larger-scale biomedical purposes of the LbL strategy corresponding to engineered tissues and implant coatings.
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Additional resources for Layer-by-layer films for biomedical applications
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Further, the large PEI molecule led to smoother surfaces in comparison to HEP, which was also observed elsewhere . The bioactivity of PEM prepared from HEP and PEI toward cells was studied with human dermal ﬁbroblasts (HDFs). 0 μg ml –1 pFN. 0 (c, d). 0. This is in line with our previous observations for HEP/CHI PEM-5 and indicates that adsorption of HEP under conditions when ion pairing prevails leads to unfavorable conformation of the molecules for further interactions with proteins .