Internal fixation in osteoporotic bone by Yuehuei H. An

By Yuehuei H. An

Osteoporosis impacts 28 million humans within the usa on my own. The
need for good inner fixation of this kind of bone is paramount. Metabolic
bone illnesses, corresponding to osteoporosis, osteomalacia, hyperparathyroidism, and
Paget's affliction, are typically linked to osteoporotic or tender skeleton,
especially within the aged sufferer. Orthopedic methods in aged sufferers are
costly and with the expanding age of the inhabitants those expenditures will proceed
to strengthen. nice demanding situations are usually encountered while inner fixation is
needed for fractures or osteotomies in osteoporotic bone.

This publication is designed
to current either present medical thoughts and state of the art wisdom in
pre-clinical study at the inner fixation of osteoporotic
bone.

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Extra resources for Internal fixation in osteoporotic bone

Example text

To interpret the information correctly and effectively, it is important to understand the structural level of the bone and the underlying assumptions on which the individual measurement is based. Advanced noninvasive techniques may provide the structural changes of osteoporotic bone at the ultramicrostructural level and even at the molecular level. It would be important to integrate this lowerscale information with the higher-scale structural information to evaluate the mechanical properties of osteoporotic bone because biomechanical features at each structural level are closely linked with those at the upper-level structure.

Osteoporotic fractures and related health problems and costs represent a significant and growing problem. 4 Fracture healing is a complex biological cascade characterized by the sequential expression of fibrous, cartilaginous, and bone-specific genes. Our understanding of the molecular events during fracture healing have benefited greatly with recent advances in molecular biology techniques. A thorough understanding of the cellular and molecular events and the correlating mechanical properties remains unknown.

Katz JL. Anisotropy of Young’s modulus of bone. Nature 1980;283:106–107. 4. Katz JL, Yoon HS. The structure and anisotropic mechanical properties of bone. IEEE Trans Biomed Eng 1984;31:878–884. 5. Parfitt AM. Age-related structural changes in trabecular and cortical bone: cellular mechanisms and biomechanical consequences. Calcif Tissue Int 1984; 36:S123–S128. 6. Hayes WC, Bouxsein ML. Biomechanics of cortical and trabecular bone: implications for assessment of fracture risk. In: Mow VC, Hayes WC, eds.

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