Case Files- : Microbiology, Second Edition by Eugene C. Toy, Cynthia R. Skinner DeBord

By Eugene C. Toy, Cynthia R. Skinner DeBord

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Extra resources for Case Files- : Microbiology, Second Edition

Sample text

Differential diagnosis: Listing of the possible diseases or conditions that may be responsible for the patient’s clinical presentation. DISCUSSION Characteristics of Bacillus Species Bacillus species are large, motile, facultative anaerobic, gram-positive rods with a central spore. The spore is quite resistant to extreme conditions and can survive in nature for prolonged periods of time. Bacillus anthracis is nonmotile and on Gram stain is often seen in chains. The virulent forms of B. anthracis are more likely to be surrounded by a capsule.

Its specificity is a result of the presence of herpes specific thymidine kinase in infected cells, which phosphorylates acyclovir 100 times more efficiently than by uninfected cells. Acyclovir can be used topically, orally for recurrent genital herpes, and intravenously for immunocompromised patients or herpes encephalitis. Its adverse effects include headache, nausea, and rarely nephrotoxicity with intravenous use. Valacyclovir is an analog of acyclovir and is converted to acyclovir in the body.

The most commonly associated anaerobe is B. fragilis. Patients with severe diverticulitis, appendicitis, or colonic injury often develop B. fragilis peritonitis. To increase the chances of recovery of anaerobes from a specimen, the sample must be appropriately collected to allow survival of anaerobes. Anaerobes are organisms that do not require oxygen for growth. Sensitivity of the anaerobic organism can vary from those that cannot tolerate any oxygen (strict anaerobes) to those that can grow in the presence of small amounts of oxygen (oxygen tolerant).

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