Allergy and Allergic Diseases, 2 Volume Set by A. Barry Kay, Jean Bousquet, Patrick G. Holt, Allen P.

By A. Barry Kay, Jean Bousquet, Patrick G. Holt, Allen P. Kaplan

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This quantity e-book is an exceptional reference resource on all features of hypersensitivity and allergic illnesses. masking almost each allergic , from the immunological and molecular foundation of the allergic reaction to destiny developments in allergic ailment prevention, this new foreign editorial staff (A.B.Kay, Jean Bousquet, Pat Holt and Allen Kaplan) have thoroughly revised and up-to-date the textual content, from either a systematic and scientific point of view. References will remain further to the textual content till it is going to press making this the main updated ebook on hand within the field.

This moment version comprises greater than 1,800 pages contained inside of ninety eight chapters.

The fee encompasses a totally searchable spouse CD ROM with the entire textual content and over three hundred photos from the ebook in complete colour.

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Additional info for Allergy and Allergic Diseases, 2 Volume Set

Example text

The type III Arthus-type reaction, or antigen–antibody complex reaction (mostly called immune-complex reaction), is mediated by soluble antigen and involves IgG, complement, and an inflammatory reaction which initially is neutrophilrich. Type IV reactions are subdivided into (i) classical delayed-type hypersensitivity initiated by CD4+ Th1-type lymphocytes (type IV Th1), (ii) cell-mediated eosinophilic hypersensitivity or chronic allergic reactions involving CD4 + (and sometimes CD8 +) Th2-type cells (type IV Th2) and (iii) reactions in which tissue damage is evoked by CD8 + cytotoxic T lymphocytes (type IV cytotoxic).

The dramatic changes in allergic and autoimmune disease prevalence rates among children in particular has prompted much interest in potential shared factors operative in early life that increase the risk of developing these diseases. qxd 4/1/08 14:25 Page 24 PART 1 Immunology of the Allergic Response environmental factors that increase/decrease the risk of developing allergic disease, and genetic variation that can predispose to the development of allergy. These are discussed below with a focus on the immunology of allergy and critical environmental factors.

West Mast cell granules as major source of histamine in tissues 1954 William Frankland Rosa Augustin First placebo-controlled clinical trial of desensitization (allergen-injection immunotherapy) Continued p. 1 (Cont’d ) 1957 Ernest Witebsky Experimental autoallergic thyroiditis: pathology and criteria of immune diseases 1958–60 Zoltan Ovary Herman N. Eisen Elicitation of immediate anaphylactic reactions requires bridging of antibody molecules by bi- or multivalent allergen 1960 Bernard. B. Levine Alain L.

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