Adenovirus - A Medical Dictionary, Bibliography, and by Icon Health Publications
By Icon Health Publications
It is a 3-in-1 reference ebook. It provides an entire scientific dictionary masking 1000's of phrases and expressions with regards to adenovirus. It additionally provides broad lists of bibliographic citations. eventually, it presents info to clients on how you can replace their wisdom utilizing quite a few net assets. The ebook is designed for physicians, scientific scholars getting ready for Board examinations, scientific researchers, and sufferers who are looking to familiarize yourself with learn devoted to adenovirus. in case your time is effective, this ebook is for you. First, you won't waste time looking out the web whereas lacking loads of correct details. moment, the ebook additionally saves you time indexing and defining entries. eventually, you won't waste time and cash printing 1000's of web content.
Read or Download Adenovirus - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References PDF
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Additional resources for Adenovirus - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References
Group B coxsackieviruses and many adenoviruses initiate infection by binding to the coxsackievirus and adenovirus receptor (CAR). We believe that detailed understanding of virus entry and its relation to virus tropism will require us to understand the biology of viral receptors- including their subcellular localization, their intracellular trafficking, and their interactions with other proteins that may function in virus entry, or restrict receptor accessibility to virus. This belief is grounded in the recent unexpected observation that, despite CAR expression on respiratory epithelial cells, intact respiratory epithelium is impervious to adenovirus entry.
Aim 5 will determine whether FCs induce allogeneic graft tolerance to HSCs via a Th2 cytokine (IL-4 and IL-10)-dependent mechanism. v. HSCs and various cytokine regimens to regenerate infarcted myocardium, the molecular mechanisms for HSC homing, the potential role of FCs, and the beneficial effects of FL. The results may eventually lead to the development of novel therapeutic strategies in patients with ischemic heart disease. ; Professor; Biochem & Molecular Genetics; University of Alabama at Birmingham Uab Station Birmingham, Al 35294 Timing: Fiscal Year 2002; Project Start 01-AUG-1984; Project End 31-MAY-2004 Summary: (provided by applicant): A safe oncolytic virus, suitable as a therapeutic agent, must target cancer cells for destruction but not propagate in normal tissues.
Three clinically-applicable cytokines (G-CSF, SCF, FL) will be tested, alone or in combination. Using gene targeted mice and immunologic blockade of integrins, Aim 2 will systematically investigate the role of four specific adhesion molecules (VCAM-1, ICAM1, P-selectin, and E-selectin) and three specific integrins (VLA-4, VLA-5, and LFA-1) in HSC migration to the infarcted myocardium. Aim 3 will decipher the role of SDF1/CXCR-4 interactions in HSC homing and infarct repair, using adenovirus-mediated gene transfer of SDF-1 and CXCR-4.